Por muy dulce y acaramelado que sea, el azúcar acelera el envejecimiento de tus tejidos y promueve tu resistencia a la insulina, te inflama, te oxida, te «tuesta», pone en peligro la integridad de tus neuronas productoras de dopamina y encima… arenga el crecimiento del cáncer.
Aquí dejo el audio del capítulo y abajo las referencias.
Referencias (por orden de aparición):
Furman, D., Campisi, J., Verdin, E., Carrera-Bastos, P., Targ, S., … & Slavich, G. M. (2019). Chronic inflammation in the etiology of disease across the life span. Nature Medicine, 25(12), 1822-1832. https://doi.org/10.1038/s41591-019-0675-0
BIBLIOGRAFÍA RECOMENDADA: Bredesen, D. (2021). The First Survivors of Alzheimer’s: How Patients Recovered Life and Hope in Their Own Words. Disponible en Amazon.
Pizzino, G., Irrera, N., Cucinotta, M., Pallio, G., Mannino, F., … & Bitto, A. (2017). Oxidative Stress: Harms and Benefits for Human Health. Oxidative Medicine and Cellular Longevity, 2017, 8416763. https://doi.org/10.1155/2017/8416763
Taubes, G. (2011). Is Sugar Toxic? The New York Times. https://www.nytimes.com/2011/04/17/magazine/mag-17Sugar-t.html
Rada, P., Avena, N. M., & Hoebel, B. G. (2005). Daily bingeing on sugar repeatedly releases dopamine in the accumbens shell. Neuroscience, 134(3), 737-744. https://doi.org/10.1016/j.neuroscience.2005.04.043
Nguyen, H. P., & Katta, R. (2015). Sugar Sag: Glycation and the Role of Diet in Aging Skin. Skin Therapy, 20(6), 1-5. https://pubmed.ncbi.nlm.nih.gov/27224842/
Takeuchi, M., Kikuchi, S., Sasaki, N., & Yamagishi, S. (2004). Involvement of advanced glycation end-products (AGEs) in Alzheimer’s disease. Current Alzheimer Research, 1(1), 39-46. https://doi.org/10.2174/1567205043480582
Smith, M. A., Taneda, S., Richey, P. L., Miyata, S., Yan, S. D., Stern, D., Sayre, L. M., Monnier, V. M., & Perry, G. (1994). Advanced Maillard reaction end products are associated with Alzheimer disease pathology. Proceedings of the National Academy of Sciences of the United States of America, 91(12), 5710-5714.
Reddy, V. P., Obrenovich, M. E., Atwood, C. S., Perry, G., & Smith, M. A. (2002). Involvement of Maillard reactions in Alzheimer disease. Neurotoxicity Research, 4(3), 191-209. https://doi.org/10.1080/1029840290007321
Lenoir, M., Serre, F., Cantin, L., & Ahmed, S. H. (2007). Intense sweetness surpasses cocaine reward. PloS one, 2(8), e698. https://doi.org/10.1371/journal.pone.0000698
Taubes, G. (2018). Contra el azúcar (Ensayo). Disponible en Amazon.
Yudkin, J. (1972 & 2012). Pure, White and Deadly: How Sugar Is Killing Us and What We Can Do to Stop It. Disponible en Amazon.
Lustig, R. (2014). Fat Chance: The Hidden Truth about Sugar, Obesity and Disease. Disponible en Amazon.
Perlmutter, D. (2020). Alzheimer’s: The Science of Prevention. Disponible en https://scienceofprevention.com/
Prinz, R. J., Roberts, W. A., & Hantman, E. (1980). Dietary correlates of hyperactive behavior in children. Journal of Consulting and Clinical Psychology, 48(6), 760-769. https://doi.org/10.1037/0022-006X.48.6.760
Jones, T. W., … & Tamborlane, W. V. (1995). Mechanisms underlying the adverse effects of sugar ingestion in healthy children. The Journal of Pediatrics, 126(2), 171-177. https://doi.org/10.1016/s0022-3476(95)70541-4
Zhang, L., Du Rietz, E., Kuja-Halkola, R., Dobrosavljevic, M., Johnell, K., & Chang, Z. (2022). Attention-deficit/hyperactivity disorder and Alzheimer’s disease and any dementia: A multi-generation cohort study in Sweden. Alzheimer’s & Dementia, 18(6), 1155-1163. https://doi.org/10.1002/alz.12462
Dobrosavljevic, M., Zhang, L., Garcia-Argibay, M., Rietz, E. D., & Larsson, H. (2022). Attention-deficit/hyperactivity disorder as a risk factor for dementia and MCI. European Psychiatry, 65(1). https://doi.org/10.1192/j.eurpsy.2021.2261
Curtin, K., Fleckenstein, A. E., Keeshin, B. R., Yurgelun-Todd, D. A., … & Hanson, G. R. (2018). Increased risk of diseases of the basal ganglia and cerebellum in patients with a history of ADHD. Neuropsychopharmacology, 43(13), 2548-2555. https://doi.org/10.1038/s41386-018-0207-5
Fan, H.-C., Chang, Y.-K., Tsai, J.-D., Chiang, K.-L., Shih, J.-H., Yeh, K.-Y., Ma, K.-H., & Li, I.-H. (2020). The Association Between Parkinson’s Disease and Attention-Deficit Hyperactivity Disorder. Cell Transplantation, 29, 963689720947416. https://doi.org/10.1177/0963689720947416
Sadasivan, S., Pond, B. B., Pani, A. K., Qu, C., Jiao, Y., & Smeyne, R. J. (2012). Methylphenidate Exposure Induces Dopamine Neuron Loss and Activation of Microglia in the Basal Ganglia of Mice. PLOS ONE, 7(3), e33693. https://doi.org/10.1371/journal.pone.0033693
Johnson, R. J., Gold, M. S., Johnson, D. R., Ishimoto, T., Lanaspa, M. A., Zahniser, N. R., & Avena, N. M. (2011). Attention-deficit/hyperactivity disorder: Is it time to reappraise the role of sugar consumption? Postgraduate Medicine, 123(5), 39-49. https://doi.org/10.3810/pgm.2011.09.2458
